Application of an amnion chorion amnion (ACA) four-layer placental allograft on a complex wound: a clinical experience case report
DOI:
https://doi.org/10.63676/fe4sxm48Keywords:
CAMPs, pressure ulcer, pressure injury, amnion-chorion-amnion, wound covering, placental allograftAbstract
Aims: Dehydrated four-layer placental amnion chorion amnion (ACA) allografts may be used as a protective barrier in wound care applications. Since cellular, acellular, and matrix-like products (CAMPs) have the potential to offer supportive measures as a wound cover from the surrounding environment, four-layer ACA allografts may serve as viable adjuncts to standard of care (SOC) for complex wounds. The objective of this case report was to evaluate the application of the allograft to a stage 4 sacral pressure wound for a paraplegic patient with significant comorbidities.
Case presentation: During home care wound services from the single provider group, data were collected from a patient who received SOC followed by application of ACApatchTM for 8 weeks. Evaluation measurements included percent area reduction (PAR), surface area (SA), and weekly changes in wound characteristics. Trends for SA, PAR, wound volume (WV) and percent wound volume (PVR) all depict the wound decreased in size as ACA applications continued. High R2 values for each, 0.92, 0.88, 0.90, 0.84 (respectively) depict a linear relationship underscoring the consistency and reliability of the observed trends across application duration.
Conclusions: Results suggest that four-layer placental allografts may be promising adjuncts to SOC for the management of complex wounds like pressure ulcers.
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